SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09030

Signal sequence   MKSLPILLLLCVAVCSA

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P08254,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09030.cif

Structure  SPKB09030.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1774.31184

Aliphatic index  183.5294118

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  586.61

Aromaticity  0

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -1.984

Hydropathy 



Literature Information


Title  The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin.

DOI  ,

Publication Year  1988

PubMed ID  3360803,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.