SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09027

Signal sequence   MTLGRRLACLFLACVLPALLLGGTALA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P08246,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7CBK,

Predicted Structure ID  SPKB09027.cif

Structure  SPKB09027.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2758.48084

Aliphatic index  159.2592593

Isoelectric point  8.834915637

Charge (pH=7)   1.874028245

Topological polar surface area  975.39

Aromaticity  0.037037037

Average rotatable bonds  3.259259259

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -5.28256

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.