SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08984

Signal sequence   MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEA

Length  42

Organism  Homo sapiens (Human)

UniProt ID  P07686,

Motif  1..42



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3LMY,

Predicted Structure ID  SPKB08984.cif

Structure  SPKB08984.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4342.46824

Aliphatic index  176.6666667

Isoelectric point  4.25810809

Charge (pH=7)   -1.060443482

Topological polar surface area  1493.19

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  54

X logP energy  -5.04033

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.