SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08869

Signal sequence   MSWKMALQIPGGFWAAAVTVMLVMLSTPVAEA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P05538,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08869.cif

Structure  SPKB08869.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3408.15354

Aliphatic index  103.75

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  1166.75

Aromaticity  0.09375

Average rotatable bonds  3.28125

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  44

X logP energy  -5.6613

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.