SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08847

Signal sequence   MGKISSLPTQLFKCCFCDFLK

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P05019,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8EYR,

Predicted Structure ID  SPKB08847.cif

Structure  SPKB08847.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2409.96334

Aliphatic index  74.28571429

Isoelectric point  8.518183718

Charge (pH=7)   1.811621534

Topological polar surface area  855.67

Aromaticity  0.142857143

Average rotatable bonds  3.80952381

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -5.8205

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.