SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08835

Signal sequence   MEAPAAGLFLLLLLGTWAPAPGS

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P04843,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6S7O,

Predicted Structure ID  SPKB08835.cif

Structure  SPKB08835.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2296.75264

Aliphatic index  123.4782609

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  770.7

Aromaticity  0.086956522

Average rotatable bonds  2.869565217

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  28

X logP energy  -3.1895

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.