SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08799

Signal sequence   MEHSTFLSGLVLATLLSQVSP

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P04234,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6JXR,

Predicted Structure ID  SPKB08799.cif

Structure  SPKB08799.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2230.60434

Aliphatic index  125.2380952

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  866.98

Aromaticity  0.047619048

Average rotatable bonds  3.380952381

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -8.383

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.