SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08742

Signal sequence   MRALTLLALLALAALCIAGQAGA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P02818,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9BUR,

Predicted Structure ID  SPKB08742.cif

Structure  SPKB08742.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2225.77934

Aliphatic index  170.4347826

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  828.74

Aromaticity  0

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -5.55283

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.