SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08662

Signal sequence   MGPWGWKLRWTVALLLAAAGT

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P01130,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9BD8,

Predicted Structure ID  SPKB08662.cif

Structure  SPKB08662.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2298.77704

Aliphatic index  107.1428571

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  812.28

Aromaticity  0.142857143

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -2.50633

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.