SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08638

Signal sequence   MHSWERLAVLVLLGAAACAA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P00746,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6QMR,

Predicted Structure ID  SPKB08638.cif

Structure  SPKB08638.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2082.50964

Aliphatic index  137

Isoelectric point  7.360093818

Charge (pH=7)   0.028690486

Topological polar surface area  780.12

Aromaticity  0.05

Average rotatable bonds  3.25

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  27

X logP energy  -4.65023

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.