SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08635

Signal sequence   MGRPLHLVLLSASLAGLLLLGESLFIRREQA

Length  31

Organism  Homo sapiens (Human)

UniProt ID  P00742,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9CLI,

Predicted Structure ID  SPKB08635.cif

Structure  SPKB08635.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3375.07914

Aliphatic index  157.4193548

Isoelectric point  10.31041611

Charge (pH=7)   1.092433702

Topological polar surface area  1320.29

Aromaticity  0.032258065

Average rotatable bonds  3.677419355

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  43

X logP energy  -8.71109

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.