SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08632

Signal sequence   MAHVRGLQLPGCLALAALCSLVHS

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P00734,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8RTN,

Predicted Structure ID  SPKB08632.cif

Structure  SPKB08632.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2460.99954

Aliphatic index  138.3333333

Isoelectric point  8.253842539

Charge (pH=7)   1.055849738

Topological polar surface area  926.64

Aromaticity  0

Average rotatable bonds  3.25

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  34

X logP energy  -7.95643

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.