General Information
SPKB ID SPKB08611
Signal sequence MAKDSQKNLNVSNNNNVQCTMGRSSQNINKSDSKGKIKRCTYAYKILLCTIFIWICQCFYNKSYYVYKKDGRRNKGKKILGIRINKSLAEMDHTKYHPEYYDEVQENYDPYYGVNQYSDECESYKSEDDDSEEEYYNSTPRVTVLEPQTENSEDEENYEKTIVDELNELPNDKKALILSYIRNGNDNNMQLLPYANNNKQNTQENISRNKEFFRHFVDFIKGYKLFDSPVLNALLPFIFIAFVYCTITMLVGNVRYIIALYILAKILKMHYDYKHKENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKKSKKN
Length 100
Organism Plasmodium falciparum (isolate 3D7)
UniProt ID O97336,
Motif 1..NA
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location Host cytoplasm
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB08611.cif
Physicochemical Information
Molecular weight 37389.41774
Aliphatic index 65.17350158
Isoelectric point 8.217206161
Charge (pH=7) 3.033135033
Topological polar surface area 16514.98
Aromaticity 0.113564669
Average rotatable bonds 3.154574132
Number of hydrogen bond donors 551
Number of hydrogen bond acceptors 544
X logP energy -293.2122
Hydropathy
Literature Information
Title Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1.
DOI 10.1371/journal.ppat.1009882,
Publication Year 2022
PubMed ID 35930605,
Patent ID NA,