SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08586

Signal sequence   MDPPAGAARRLLCPALLLLLLLLPPPLLP

Length  29

Organism  Homo sapiens (Human)

UniProt ID  O95450,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08586.cif

Structure  SPKB08586.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3058.90704

Aliphatic index  175.1724138

Isoelectric point  8.54983383

Charge (pH=7)   0.936449445

Topological polar surface area  977.69

Aromaticity  0

Average rotatable bonds  3.034482759

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  35

X logP energy  -0.53556

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.