SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08566

Signal sequence   MAPAPLGVPEEQLLGCRSRVLSRLLFIAQTALLLLPAAGA

Length  40

Organism  Homo sapiens (Human)

UniProt ID  O94898,

Motif  1..40



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08566.cif

Structure  SPKB08566.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4158.03234

Aliphatic index  139.25

Isoelectric point  8.549778494

Charge (pH=7)   0.939549895

Topological polar surface area  1570.23

Aromaticity  0.025

Average rotatable bonds  3.3

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  53

X logP energy  -11.47569

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.