SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08462

Signal sequence   MRAAGTLLAFCCLVLSTTG

Length  19

Organism  Homo sapiens (Human)

UniProt ID  O76096,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08462.cif

Structure  SPKB08462.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1928.35344

Aliphatic index  113.1578947

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  729.94

Aromaticity  0.052631579

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -7.45903

Hydropathy 



Literature Information


Title  N-terminome analysis of the human mitochondrial proteome.

DOI  10.1002/pmic.201400617,

Publication Year  2015

PubMed ID  25944712,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.