SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08455

Signal sequence   MASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWG

Length  41

Organism  Homo sapiens (Human)

UniProt ID  O75899,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6WIV,

Predicted Structure ID  SPKB08455.cif

Structure  SPKB08455.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4154.07134

Aliphatic index  114.3902439

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1347.63

Aromaticity  0.024390244

Average rotatable bonds  2.634146341

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  49

X logP energy  -6.76456

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.