SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08453

Signal sequence   MGPPSAAPRGGHRPWQGLLITASLLTFWHPPTTVQ

Length  35

Organism  Homo sapiens (Human)

UniProt ID  O75871,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08453.cif

Structure  SPKB08453.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3779.38004

Aliphatic index  72.57142857

Isoelectric point  12.50011104

Charge (pH=7)   2.179795859

Topological polar surface area  1420.28

Aromaticity  0.085714286

Average rotatable bonds  3.057142857

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  49

X logP energy  -12.66876

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.