General Information
SPKB ID SPKB08450
Signal sequence MEPGRRGAAALLALLCVACALRAGRA
Length 26
Organism Homo sapiens (Human)
UniProt ID O75718,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8K0E,
Predicted Structure ID SPKB08450.cif
Physicochemical Information
Molecular weight 2611.18334
Aliphatic index 116.9230769
Isoelectric point 10.45482487
Charge (pH=7) 2.875796745
Topological polar surface area 1066.93
Aromaticity 0
Average rotatable bonds 3.269230769
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 35
X logP energy -10.50502
Hydropathy 
Literature Information
