SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08447

Signal sequence   MSRRSMLLAWALPSLLRLGAA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  O75594,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08447.cif

Structure  SPKB08447.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2313.85094

Aliphatic index  130.4761905

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  898.71

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  30

X logP energy  -6.41499

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.