SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08437

Signal sequence   MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASA

Length  44

Organism  Homo sapiens (Human)

UniProt ID  O75326,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08437.cif

Structure  SPKB08437.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4518.48544

Aliphatic index  109.0909091

Isoelectric point  13.19898313

Charge (pH=7)   5.997964432

Topological polar surface area  1674.6

Aromaticity  0.022727273

Average rotatable bonds  2.909090909

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  55

X logP energy  -13.10708

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.