SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08431

Signal sequence   MAAAGARLSPGPGSGLRGRPRLCFHPGPPPLLPLLLLFLLLLPPPPLLA

Length  49

Organism  Homo sapiens (Human)

UniProt ID  O75129,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08431.cif

Structure  SPKB08431.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5043.24414

Aliphatic index  129.5918367

Isoelectric point  12.50009851

Charge (pH=7)   4.026905429

Topological polar surface area  1671.38

Aromaticity  0.040816327

Average rotatable bonds  2.918367347

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  59

X logP energy  -7.50572

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.