SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08423

Signal sequence   MEKRAAAGLEGAPGARAQLAVVCLVNIFLTGRLSSA

Length  36

Organism  Homo sapiens (Human)

UniProt ID  O75074,

Motif  1..36



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08423.cif

Structure  SPKB08423.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3642.29574

Aliphatic index  111.3888889

Isoelectric point  9.823375461

Charge (pH=7)   1.939254861

Topological polar surface area  1506.22

Aromaticity  0.027777778

Average rotatable bonds  3.361111111

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  50

X logP energy  -16.11779

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.