SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08422

Signal sequence   MKCFFPVLSCLAVLGVVSA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  O75054,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08422.cif

Structure  SPKB08422.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1984.50394

Aliphatic index  133.1578947

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  644.81

Aromaticity  0.105263158

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  -2.7239

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.