SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08351

Signal sequence   MHRDAWLPRPAFSLTGLSLFFSLVPPGRS

Length  29

Organism  Homo sapiens (Human)

UniProt ID  O60939,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6J8G,

Predicted Structure ID  SPKB08351.cif

Structure  SPKB08351.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3256.81874

Aliphatic index  84.13793103

Isoelectric point  12.19913522

Charge (pH=7)   2.089329941

Topological polar surface area  1211.58

Aromaticity  0.137931034

Average rotatable bonds  3.310344828

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  41

X logP energy  -9.02789

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.