SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08345

Signal sequence   MSGGRAPAVLLGGVASLLLSFVWMPALLPVAS

Length  32

Organism  Homo sapiens (Human)

UniProt ID  O60888,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2ZFH,

Predicted Structure ID  SPKB08345.cif

Structure  SPKB08345.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3181.88844

Aliphatic index  137.1875

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  1097.66

Aromaticity  0.0625

Average rotatable bonds  3

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -6.77713

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.