SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08344

Signal sequence   MRWLWPLAVSLAVILAVGLSRVSGG

Length  25

Organism  Homo sapiens (Human)

UniProt ID  O60883,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08344.cif

Structure  SPKB08344.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2652.23944

Aliphatic index  152

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  969

Aromaticity  0.08

Average rotatable bonds  3.28

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  32

X logP energy  -4.90126

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.