SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08340

Signal sequence   MDFWLWPLYFLPVSGA

Length  16

Organism  Homo sapiens (Human)

UniProt ID  O60667,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08340.cif

Structure  SPKB08340.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1942.30514

Aliphatic index  97.5

Isoelectric point  3.749986963

Charge (pH=7)   -1.002419631

Topological polar surface area  591.58

Aromaticity  0.3125

Average rotatable bonds  3.25

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  21

X logP energy  2.2301

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.