SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08336

Signal sequence   MTSSGPGPRFLLLLPLLLPPAASA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  O60568,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8ZGC,

Predicted Structure ID  SPKB08336.cif

Structure  SPKB08336.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2419.95114

Aliphatic index  126.25

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  831.49

Aromaticity  0.041666667

Average rotatable bonds  2.875

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -5.65833

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.