SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08332

Signal sequence   MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRG

Length  34

Organism  Homo sapiens (Human)

UniProt ID  O60486,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08332.cif

Structure  SPKB08332.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3604.36714

Aliphatic index  97.94117647

Isoelectric point  12.3362596

Charge (pH=7)   4.998597418

Topological polar surface area  1366.58

Aromaticity  0.029411765

Average rotatable bonds  3.088235294

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  45

X logP energy  -10.21515

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.