SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08279

Signal sequence   MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATA

Length  39

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  O53168,

Motif  1..39



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  4Q4G,

Predicted Structure ID  SPKB08279.cif

Structure  SPKB08279.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4101.89684

Aliphatic index  92.82051282

Isoelectric point  12.89796747

Charge (pH=7)   6.935986404

Topological polar surface area  1702.71

Aromaticity  0.025641026

Average rotatable bonds  3.230769231

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  55

X logP energy  -19.64541

Hydropathy 



Literature Information


Title  Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System.

DOI  10.1128/mBio.02259-15,

Publication Year  2016

PubMed ID  26933057,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.