SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08249

Signal sequence   MKFISTSLLLMLLVSSLSPVQG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  O43927,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08249.cif

Structure  SPKB08249.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2364.92754

Aliphatic index  150.4545455

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  856.12

Aromaticity  0.045454545

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  33

X logP energy  -6.1629

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.