SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08248

Signal sequence   MAPAQRPLLPLLLLLLPLPPPPFA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  O43921,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08248.cif

Structure  SPKB08248.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2589.30724

Aliphatic index  158.75

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  767.29

Aromaticity  0.041666667

Average rotatable bonds  2.875

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  28

X logP energy  1.59747

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.