SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08230

Signal sequence   MGLHFKWPLGAPMLAAIYAMSMVLKMLPALGMA

Length  33

Organism  Homo sapiens (Human)

UniProt ID  O43300,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08230.cif

Structure  SPKB08230.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3562.53114

Aliphatic index  109.6969697

Isoelectric point  10.24773591

Charge (pH=7)   2.087452908

Topological polar surface area  1105.12

Aromaticity  0.090909091

Average rotatable bonds  3.393939394

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  45

X logP energy  -0.9275

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.