SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08228

Signal sequence   MRAPHLHLSAASGARALAKLLPLLMAQLWA

Length  30

Organism  Homo sapiens (Human)

UniProt ID  O43240,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08228.cif

Structure  SPKB08228.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3208.92294

Aliphatic index  130.6666667

Isoelectric point  12.51647976

Charge (pH=7)   3.179500825

Topological polar surface area  1196.16

Aromaticity  0.033333333

Average rotatable bonds  3.4

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  41

X logP energy  -7.30326

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.