SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08227

Signal sequence   MAARPLPVSPARALLLALAGALLAPCEA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  O43184,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08227.cif

Structure  SPKB08227.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2757.39164

Aliphatic index  140

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  995.19

Aromaticity  0

Average rotatable bonds  2.928571429

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  35

X logP energy  -6.63156

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.