SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08109

Signal sequence   MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTC

Length  37

Organism  Homo sapiens (Human)

UniProt ID  O15520,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08109.cif

Structure  SPKB08109.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4131.10994

Aliphatic index  102.7027027

Isoelectric point  7.720032341

Charge (pH=7)   0.745684436

Topological polar surface area  1300.66

Aromaticity  0.135135135

Average rotatable bonds  3.243243243

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  54

X logP energy  -5.4315

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.