SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08074

Signal sequence   MLRAGWLRGAAALALLLAARVVAA

Length  24

Organism  Homo sapiens (Human)

UniProt ID  O14657,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08074.cif

Structure  SPKB08074.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2435.01814

Aliphatic index  159.1666667

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  934.11

Aromaticity  0.041666667

Average rotatable bonds  3.25

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  29

X logP energy  -5.15389

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.