General Information
SPKB ID SPKB08073
Signal sequence MKLGRAVLGLLLLAPSVVQA
Length 20
Organism Homo sapiens (Human)
UniProt ID O14656,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB08073.cif
Physicochemical Information
Molecular weight 2049.58944
Aliphatic index 175.5
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 758.67
Aromaticity 0
Average rotatable bonds 3.4
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -3.91403
Hydropathy
Literature Information
Title Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulum.
DOI 10.1042/BJ20061313,
Publication Year 2007
PubMed ID 17037984,
Patent ID NA,