SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB08071

Signal sequence   MALAGLCALLACCWGPAAVLA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  O14525,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB08071.cif

Structure  SPKB08071.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2018.53914

Aliphatic index  140

Isoelectric point  5.759310256

Charge (pH=7)   -0.187939848

Topological polar surface area  652.32

Aromaticity  0.047619048

Average rotatable bonds  2.80952381

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.8444

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.