SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07989

Signal sequence   MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARA

Length  49

Organism  Homo sapiens (Human)

UniProt ID  O00754,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07989.cif

Structure  SPKB07989.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5049.04264

Aliphatic index  92.04081633

Isoelectric point  9.660623644

Charge (pH=7)   3.811639665

Topological polar surface area  1879.91

Aromaticity  0.081632653

Average rotatable bonds  3.102040816

Number of hydrogen bond donors  70

Number of hydrogen bond acceptors  66

X logP energy  -16.79755

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.