SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07988

Signal sequence   MLEEPRPRPPPSGLAGLLFLALCSRALS

Length  28

Organism  Homo sapiens (Human)

UniProt ID  O00744,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07988.cif

Structure  SPKB07988.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2992.59084

Aliphatic index  108.2142857

Isoelectric point  8.549778494

Charge (pH=7)   0.939549895

Topological polar surface area  1126.06

Aromaticity  0.035714286

Average rotatable bonds  3.25

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  39

X logP energy  -8.91399

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.