SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07977

Signal sequence   MILANVFCLFFFLDETLRSLA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  O00451,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5MR4,

Predicted Structure ID  SPKB07977.cif

Structure  SPKB07977.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2463.97834

Aliphatic index  134.7619048

Isoelectric point  4.184374695

Charge (pH=7)   -1.061772121

Topological polar surface area  865.37

Aromaticity  0.19047619

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -2.42833

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.