General Information
SPKB ID SPKB07977
Signal sequence MILANVFCLFFFLDETLRSLA
Length 21
Organism Homo sapiens (Human)
UniProt ID O00451,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5MR4,
Predicted Structure ID SPKB07977.cif
Physicochemical Information
Molecular weight 2463.97834
Aliphatic index 134.7619048
Isoelectric point 4.184374695
Charge (pH=7) -1.061772121
Topological polar surface area 865.37
Aromaticity 0.19047619
Average rotatable bonds 3.761904762
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 30
X logP energy -2.42833
Hydropathy
Literature Information