SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07975

Signal sequence   MEKMLAGCFLLILGQIVLLPAEA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  O00339,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07975.cif

Structure  SPKB07975.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2474.11634

Aliphatic index  161.3043478

Isoelectric point  4.258107901

Charge (pH=7)   -1.060735205

Topological polar surface area  838.44

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  31

X logP energy  -1.2798

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.