SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07969

Signal sequence   MAPPPARVHLGAFLAVTPNPGSA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  O00220,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07969.cif

Structure  SPKB07969.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2271.66544

Aliphatic index  80.86956522

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  833.7

Aromaticity  0.043478261

Average rotatable bonds  2.652173913

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  30

X logP energy  -8.16523

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.