SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07953

Signal sequence   MKFNIIIVFISLAILVHSSYA

Length  21

Organism  Dermatophagoides pteronyssinus (European house dust mite)

UniProt ID  L7N6F8,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07953.cif

Structure  SPKB07953.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2379.92924

Aliphatic index  167.1428571

Isoelectric point  9.300695891

Charge (pH=7)   1.087747942

Topological polar surface area  824.03

Aromaticity  0.142857143

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -2.0973

Hydropathy 



Literature Information


Title  Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets.

DOI  10.4049/jimmunol.1202288,

Publication Year  2013

PubMed ID  23460742,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.