SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07945

Signal sequence   MKWDKRVVALILAVMIVCPLFAAPAHA

Length  27

Organism  Paenibacillus alvei (strain ATCC 6344 / DSM 29 / NBRC 3343 / NCIMB 9371 / NCTC 6352) (Bacillus alvei)

UniProt ID  K4ZRC1,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07945.cif

Structure  SPKB07945.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2964.72804

Aliphatic index  137.4074074

Isoelectric point  9.674862095

Charge (pH=7)   2.02677178

Topological polar surface area  998.05

Aromaticity  0.074074074

Average rotatable bonds  3.407407407

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -1.64613

Hydropathy 



Literature Information


Title  Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family.

DOI  10.1074/jbc.RA118.003244,

Publication Year  2018

PubMed ID  29794027,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.