SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB07411

Signal sequence   MEGSWFHRKRFSFYLLLGFLLQGRG

Length  25

Organism  Homo sapiens (Human)

UniProt ID  A5X5Y0,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB07411.cif

Structure  SPKB07411.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3046.58834

Aliphatic index  78

Isoelectric point  11.43079974

Charge (pH=7)   3.089513131

Topological polar surface area  1158.99

Aromaticity  0.24

Average rotatable bonds  4

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  37

X logP energy  -5.81469

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.