General Information
SPKB ID SPKB07145
Signal sequence MKLSIVLVALAAVSSA
Length 16
Organism Yarrowia lipolytica JMY2101
UniProt ID NA,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 1.35(U/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07145.cif
Physicochemical Information
Molecular weight 1572.96714
Aliphatic index 176.875
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 586.53
Aromaticity 0
Average rotatable bonds 3.25
Number of hydrogen bond donors 21
Number of hydrogen bond acceptors 22
X logP energy -4.2387
Hydropathy
Literature Information
Title Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
DOI 10.1007/s00253-018-8966-9,
Publication Year 2018
PubMed ID 29704042,
Patent ID NA,