General Information
SPKB ID SPKB07142
Signal sequence MKLSTILFTACATLAAA
Length 17
Organism Yarrowia lipolytica JMY2101
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency alpha-amylase yield: 4.17(U/mL)
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB07142.cif
Physicochemical Information
Molecular weight 1726.12244
Aliphatic index 121.1764706
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 635.86
Aromaticity 0.058823529
Average rotatable bonds 3.235294118
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 25
X logP energy -5.3717
Hydropathy
Literature Information
Title Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags
DOI 10.1007/s00253-018-8966-9,
Publication Year 2018
PubMed ID 29704042,
Patent ID NA,